Mechanical properties and drug release behavior of PCL/zein coated 45S5 bioactive glass scaffolds for bone tissue engineering application
نویسندگان
چکیده
منابع مشابه
Bioactive Glass Scaffolds for Bone Tissue Engineering
In materials science, the ability to develop porous constructs with high mechanical strength is important for a broad range of emerging applications, including filters, catalyst support, and tissue engineering scaffolds. Particularly for orthopedic surgery, the regeneration of large bone defects in load-bearing limbs remains a challenging problem that require scaffolds that combine the strength...
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Traditionally, bioactive glasses have been used to fill and restore bone defects. More recently, this category of biomaterials has become an emerging research field for bone tissue engineering applications. Here, we review and discuss current knowledge on porous bone tissue engineering scaffolds on the basis of melt-derived bioactive silicate glass compositions and relevant composite structures...
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Objective(s): The present study aimed to prepare polycaprolactone (PCL) scaffolds with high porosity and pore interconnectivity, in order to copy the microstructure of natural bones using the thermally induced phase separation (TIPS) technique. Materials and Methods: The scaffolds were coated with chitosan (CH), bioactive glass (BG), and gelatin nanoparticles (GEL NPs) and assessed using ...
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It is of great importance to prepare multifunctional scaffolds combining good mechanical strength, bioactivity, and drug delivery ability for bone tissue engineering. In this study, nanosized mesoporous bioglass/poly(lactic-co-glycolic acid) composite-coated calcium silicate scaffolds, named NMBG-PLGA/CS, were successfully prepared. The morphology and structure of the prepared scaffolds were ch...
متن کاملEvaluation of cytotoxicity and mechanical properties of fluorapatite-45S5 bioactive glass nanocomposite
The purpose of this study was to fabricate and characterize nanocomposite powder from 45S5 bioactive glass/ fluorapatite. Nanocomposites containing 10, 15 and 20 wt.% of fluorapatite were synthesized by sol-gel method. XRD and FT-IR analyses were used to characterize and evaluate the produced nanocomposites. The results of XRD and FT-IR analysis indicated the successful synthesis of high purity...
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ژورنال
عنوان ژورنال: Data in Brief
سال: 2015
ISSN: 2352-3409
DOI: 10.1016/j.dib.2015.07.013